Invalid handle error

Hello Gurus,

I am supporting Biztalk 2013 at client location and one of the application that has been working fine for years has crashed today with following reason.

We have researched all documentations but could not get any help on this.

Any help will be appreciated. This is kind of urgent as currently a main process has failed in production and has severity 1

Log Name:      ApplicationSource:        BizTalk ServerDate:          10/29/2014 5:15:46 AMEvent ID:      5719Task Category: BizTalk ServerLevel:         ErrorKeywords:      ClassicUser:          N/AComputer:      VLCME2BTHOST01P.MGMMIRAGE.orgDescription:

There was a failure executing the receive pipeline: “Microsoft.BizTalk.DefaultPipelines.XMLReceive, Microsoft.BizTalk.DefaultPipelines, Version=3.0.1.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35” Source: “Pipeline ” Receive Port: “CC Settlement Receive Port” URI: “BT2013SQL01P:CME2ADMIN”

Reason: Invalid handle.Parameter name: handleEvent Xml:<Event xmlns=”http://schemas.microsoft.com/win/2004/08/events/event”>&nbsp; <System>    <Provider Name=”BizTalk Server” />    <EventID Qualifiers=”49344″>5719</EventID>    <Level>2</Level>    <Task>1</Task>    <Keywords>0x80000000000000</Keywords>    <TimeCreated SystemTime=”2014-10-29T12:15:46.000000000Z” />    <EventRecordID>553485</EventRecordID>    <Channel>Application</Channel>    <Computer>VLCME2BTHOST01P.MGMMIRAGE.org</Computer>    <Security />  </System>  <EventData>    <Data>Microsoft.BizTalk.DefaultPipelines.XMLReceive, Microsoft.BizTalk.DefaultPipelines, Version=3.0.1.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35</Data>    <Data>Pipeline </Data>    <Data>CC Settlement Receive Port</Data>    <Data>BT2013SQL01P:CME2ADMIN</Data>    <Data>Invalid handle.Parameter name: handle</Data>  </EventData></Event>