configuring problem with biztalk server 2010

It could be a few things.  First make sure the Name of the SQL Server you are using is correct.

If the SQL Server you are using is local:

– Make sure you are running as a local administrator

– Make sure the SQL Server is running

If the SQL is remote:

– Make sure MSDTC is setup correctly

– Make sure you are using domain groups and users are in the right groups

Just a few things I can think of off the top.  

Here is a link to an 8 part blog post on how to install and configure BizTalk: sandroaspbiztalkblog.wordpress.com/…/biztalk-2010-installation-and-configuration-enable-internet-information-services-part-1

Hope this helps./