Hi Sree,
Normally, developers with experience in .NET (C# language, ASP.NET) have an easier transition learning BizTalk. You would also need to add SQL Server, IIS and Web Services (SOAP, REST, WCF) as the other skills to be acquired, as BizTalk databases reside in SQL Server platform, and a lot of real-world business scenarios involve passing data from/to SQL Server data repositories and consuming web services in BizTalk or exposing BizTalk orchestrations as web services.
If you are indeed serious about pursuing a career in BizTalk, you should look into acquiring those other skill sets.
Daniel.