You need to create a 32 bit host and its subsequent host instance, otherwise you will get the following error.
Event Type: Error
Event Source: BizTalk Server 2006
Event Category: BizTalk Server 2006
Event ID: 5754
Date: 6/12/2009
Time: 7:37:50 PM
User: N/A
Computer: HAL64
Description:
A message sent to adapter “HTTP” on send port “SendPort4” with URI http://server/BTSHTTPReceive.dll is suspended.
Error details: There was a failure executing the send pipeline: “Microsoft.BizTalk.EdiInt.DefaultPipelines.AS2Send, Microsoft.BizTalk.Edi.EdiIntPipelines, Version=3.0.1.0, Culture=neutral, PublicKeyToken=31bf3856ad364e35” Source: “Unknown ” Send Port: “SendPort4” URI: http://server/BTSHTTPReceive.dll Reason: Retrieving the COM class factory for component with CLSID {254B4003-2AA7-4C82-BB2E-18BA7F22DCD2} failed due to the following error: 80040154.
MessageId: {9B3DB552-386E-4C46-859F-732AC39E1281}
InstanceID: {24442524-9A98-4778-A29A-93FA21AFC92B}
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