Object reference not set to an instance of an object.

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#13590

Presumably CISCOVLN_VA._3B18R11.Validate is your own .DOT code?
In Biztalk, after you declare a variable (in Orchestration Viewer), you still must instantiate it (if the class is not static) in an expression shape before you use it the first time.

CISCOVLN_VA = new yourClassName();

Or the error could be coming from the C# code – hopefully it has been unit tested first!

Neal Walters
http://Biztalk-Training.com