MQRC 2072 – Transactional issue
You may have issues with the IBM MQ Client 7.5 and 8.0 together with BizTalk 2013 / 2013 R2 with Transactional Support set to true. You are getting an MQRC 2072 and you can see a lot of errors / warnings in the Event Log. This is actually a code defect in the 220.127.116.11 / 18.104.22.168 and 22.214.171.124 client.
IBM has worked on fixing this issues : http://www-01.ibm.com/support/docview.wss?rs=171&uid=swg1IT07469
The issue is finally fixed in the following IBM MQ Clients :