Root element is missing

I am trying to troubleshoot an issue that we are receiving every now and then.  Sometimes we will receive the error “Root Element is missing” when trying to transmit data.  Sometimes during the retry period the data will be successfully transmitted, but other times it will go into a dehydrated state.

I have noticed that it doesn’t happen quite as frequent when we are transmitting messages from the local dev environment (1 BizTalk instance), but it seems to be compounded when we are using our UAT environment (2 BizTalk instances).

• We are trying to send/receive from two ODBC sources
• We are using the ODBC adapter from TwoConnect
• If I look at the xml message in Binary mode, I can see it is prefixed with the BOM

Not exactly sure where to start troubleshooting.  I have set the TwoConnect adapter up in Debug mode and attached it to the BtsNtSvc to verify I didn’t get any errors from the adapter.