Re: Error : The message found multiple request response subscriptions. A message can only be routed to a single request response subscription

There is some other service (orchestration or 2 way send port) in your BizTalk environment that has the same subscription as the orchestration you published.  Are there any other orchestrations that are sharing the receive port that was generated when you published the orchestration?  Are there any services using the same message type?  You could debug this by running a query for all subscriptions in the group hub page.