Hello.
Well, Biztalk does not support Excel files so you will either need to build a custom adapter, buy one (do not even know if one exists), or transform your Excel file into Xml to send it into Biztalk by some other external project.
What I have done in the past was to use a C# component to read the Excel document and send Xml messages to Biztalk. Then, we just used an Xml Receive Port and in your case a SQL Send Port. You can define your map and use it on the Receive Port (or Send).
Hope this helps.