Off course you make backups of your BizTalk databases! You have set the Recovery Model from the databases to Full and every single day your Maintenance Plans or (actually) the SQL Server Agent jobs make Full and Log backups. So in case you need to restore your BizTalk databases, you are safe…
Well, I’ve got some news for you… You’re not so safe…

If you make BizTalk Backups like described above, you could be in deep trouble in case you need to restore. When it comes to making backups from your BizTalk databases, Microsoft supports only one way….

Read this very nice written blog on how to backup Biztalk Databases the right way: Backup BizTalk: Don’t make ordinary Full backups